Nano(bio)chemistry on surfaces is the core activity of the group. To please our “seeing is believing” desire, we use high-resolution scanning probe microscopy techniques such as scanning tunneling microscopy and atomic force microscopy, sometimes combined with optical microscopy techniques, to unravel the beauty and function of multi-(bio)molecular assemblies on surfaces. The liquid-solid interface is our preferred playground.
Molecular self-assembly on surfaces is a central research theme, with a focus on the relation between structure and function. Recent activities cover a broad range of topics such as two-dimensional crystal engineering (e.g. formation of nanoporous surfaces, chirality at interfaces), templating, dynamics and on-surface reactivity. In addition to the non-covalent supramolecular chemistry approach, we recently put more on more emphasis on the functionalization of surfaces using covalent chemistry. Whatever the functionalization approach, nanostructuring is the keyword: we aim at spatially controlling the ordering of molecules on surfaces, via bottom-up approaches as well as nanolithography. These approaches are not only ideal to decorate and functionalize “traditional” surfaces such as “graphite and gold, but bring clear advantages for the controlled functionalization of 2D materials (graphene, MoS2, …).
Another major research line is the study of interactions of DNA with proteins and multi-protein complexes, to unravel their structural and functional importance in diseases such as HIV and cancer.
All of this is made possible thanks to team of enthusiastic researchers, who thrive in a stimulating environment. I aim at bringing together researchers with different scientific and cultural backgrounds (physical chemists, synthetic chemists, biochemists, physicists, engineers), and to activate them to work together, to exchange ideas, and to learn from each other. This strong believe in the power of collaboration is exemplified by the many national and international collaborations. The research team is very well equipped and moved in 2015 to state-of-the-art research facilities (Leuven Chem&Tech and Leuven Nanocentre).
You want to joint this international team? Contact me!
Kind regards,-Steven De Feyter